牛樟芝（Antrodia cinnamomea）是台灣特有真菌，三十年來累積了 1,281 篇同儕審查研究、23,731 次引用。這份索引把它們整理成一份可以查得動的東西：每一筆都標明做在人身上、動物身上，還是細胞上，用的是子實體、菌絲體還是單一化合物，以及被同行引用了幾次。

這是文獻導覽，不是產品說明。列出一篇研究不代表任何產品具有該效果。

這些研究集中在哪裡

全部 1,281 篇依主題歸類，每篇只歸一類。由多到少排序。

這份索引可以幫你做什麼

怎麼看

人體研究（全部 25 篇）

這是證據層級最高的一層，也是最小的一層。全數列出，不挑選。

• Identification of antrocin from Antrodia camphorata as a selective and novel class of small molecule inhibitor of Akt/mTOR signaling in metastatic breast cancer MDA-MB-231 cells.
  人體單一化合物Chemical research in toxicology201161 次引用
• Metabolites identification and multi-component pharmacokinetics of ergostane and lanostane triterpenoids in the anticancer mushroom Antrodia cinnamomea.
  人體萃取物Journal of pharmaceutical and biomedical analysis201542 次引用
• A preliminary randomised controlled study of short-term Antrodia cinnamomea treatment combined with chemotherapy for patients with advanced cancer.
  人體萃取物BMC complementary and alternative medicine201638 次引用
• Effectiveness of a novel herbal agent MB-6 as a potential adjunct to 5-fluoracil-based chemotherapy in colorectal cancer.
  人體菌絲體Nutrition research (New York, N.Y.)201435 次引用
• 4-Hydroxybenzoic acid serves as an endogenous ring precursor for antroquinonol biosynthesis in Antrodia cinnamomea.
  人體菌絲體Phytochemistry201917 次引用
• A phase I multicenter study of antroquinonol in patients with metastatic non-small-cell lung cancer who have received at least two prior systemic treatment regimens, including one platinum-based chemotherapy regimen.
  人體單一化合物Molecular and clinical oncology201519 次引用
• Hepatoprotective Effect of Antrodia cinnamomea Mycelium in Patients with Nonalcoholic Steatohepatitis: A Randomized, Double-Blind, Placebo-Controlled Trial.
  人體菌絲體Journal of the American College of Nutrition202112 次引用
• A Botanical Drug Extracted From Antrodia cinnamomea: A First-in-human Phase I Study in Healthy Volunteers.
  人體萃取物Journal of the American Nutrition Association20239 次引用
• Antroquinonol administration in animal preclinical studies for Alzheimer's disease (AD): A new avenue for modifying progression of AD pathophysiology.
  人體單一化合物Brain, behavior, & immunity - health20229 次引用
• Antrodia cinnamomea is a potentially effective complementary medicine for adjuvant therapy against breast cancer with bone metastasis: A case report.
  人體萃取物Medicine20208 次引用
• Anti-cachectic effect of Antrodia cinnamomea extract in lung tumor-bearing mice under chemotherapy.
  人體萃取物Oncotarget20188 次引用
• Effects of Antrodia Camphorata Mycelia Extract Containing Antroquinonol on Lowering Low-Density Lipoprotein Cholesterol: A Randomized Double-Blind Study
  人體菌絲體20177 次引用
• A Pilot Study to Assess Food Safety and Potential Cholesterol-Lowering Efficacy of Antrodia cinnamomea Solid-State Cultivated Mycelium in Healthy Adults.
  人體菌絲體Evidence-based complementary and alternative medicine : eCAM20206 次引用
• Antrodia cinnamomea Suppress Dengue Virus Infection through Enhancing the Secretion of Interferon-Alpha.
  人體萃取物Plants (Basel, Switzerland)20224 次引用
• Naturally Occurring Plant-Based Anticancerous Candidates as Potential ERK2 Inhibitors: In-Silico Database Mining and Molecular Dynamics Simulations.
  人體萃取物Chemistry & biodiversity20243 次引用
• Hepatoprotective effect of Antrodia Cinnamomea mycelia extract in subhealth Japanese adults: a randomized, double-blind, placebo-controlled clinical study.
  人體菌絲體Journal of dietary supplements20233 次引用
• Taiwanofungus camphoratus Combined With Amphotericin B for Metastatic Cancer Patients Unresponsive to or Unwilling to Undergo Chemotherapy: A Pilot Study.
  人體萃取物Alternative therapies in health and medicine20203 次引用
• UPro1A8: A Specific Fluorescent Probe for Functional Imaging and Inhibitor Screening of UGT1A8.
  人體萃取物Journal of medicinal chemistry20262 次引用
• Protective Effect of Antrodia Camphorate on the Tissues of Brain, Kidney, Lung, and Liver Is Correlated with Declining Lipid Peroxidation
  人體萃取物20181 次引用
• Clinical Benefits of Antrodia Camphorata Containing Antroquinonol on Daily Fatigue and Alcohol Syndrome
  人體單一化合物20190 次引用
• A Phase II, Placebo-controlled Trial Evaluating the Efficacy of Antroquinonol in Patients With Atopic Dermatitis
  人體單一化合物Case Medical Research20190 次引用
• A phase I/II study of antroquinonol in combination with nab-paclitaxel and gemcitabine for patients with metastatic pancreatic cancer.
  人體單一化合物Journal of Clinical Oncology20240 次引用
• Phase II multicenter study of antroquinonol in patients with stage IV non-small cell lung cancer who have failed at least two lines of anti-cancer therapy.
  人體單一化合物Journal of Clinical Oncology20190 次引用
• The potential treatment of antroquinonol in adult patients with relapsed acute myeloid leukemia (AML).
  人體單一化合物20210 次引用
• A Randomized, Placebo-controlled Trial of Antroquinonol in Patients With Chronic Hepatitis B
  人體單一化合物Case Medical Research20190 次引用

依主題

成分化學、鑑定與栽培

387 篇，是篇數最多的一類。它不談功效，談的是這個菇裡有什麼分子、怎麼鑑定、怎麼栽培——也是子實體與菌絲體差異的判斷依據。

• Recent progress of research on medicinal mushrooms, foods, and other herbal products used in traditional Chinese medicine.
  綜述菌絲體Journal of traditional and complementary medicine201282 次引用
• The vasorelaxation of Antrodia camphorata mycelia: involvement of endothelial Ca(2+)-NO-cGMP pathway.
  動物菌絲體Life sciences200381 次引用
• Current Advances on the Structure, Bioactivity, Synthesis, and Metabolic Regulation of Novel Ubiquinone Derivatives in the Edible and Medicinal Mushroom Antrodia cinnamomea.
  綜述萃取物Journal of agricultural and food chemistry201740 次引用
• Antihypertensive activities of a solid-state culture of Taiwanofungus camphoratus (Chang-chih) in spontaneously hypertensive rats.
  動物萃取物Bioscience, biotechnology, and biochemistry200745 次引用
• A Review of the Potential Benefits of Herbal Medicines, Small Molecules of Natural Sources, and Supplements for Health Promotion in Lupus Conditions.
  綜述萃取物Life (Basel, Switzerland)202318 次引用
• Contents of lovastatin, γ-aminobutyric acid and ergothioneine in mushroom fruiting bodies and mycelia
  其他子實體LWT.2012211 次引用

癌症與腫瘤研究

337 篇，是這個領域數量最多的主題，也是唯一有註冊臨床試驗的方向（見上方人體研究）。列在這裡是因為它客觀上是這個領域的主體；這與任何產品訴求無關。

• A review on the effects of current chemotherapy drugs and natural agents in treating non-small cell lung cancer.
  綜述萃取物BioMedicine2017396 次引用
• Review of Pharmacological Effects of Antrodia camphorata and Its Bioactive Compounds.
  綜述萃取物Evidence-based complementary and alternative medicine : eCAM2011365 次引用
• Antcin K Inhibits TNF-α, IL-1β and IL-8 Expression in Synovial Fibroblasts and Ameliorates Cartilage Degradation: Implications for the Treatment of Rheumatoid Arthritis.
  動物單一化合物Frontiers in immunology202163 次引用
• Antrodia salmonea suppresses invasion and metastasis in triple-negative breast cancer cells by reversing EMT through the NF-κB and Wnt/β-catenin signaling pathway.
  動物萃取物Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association201959 次引用
• A sesquiterpene lactone antrocin from Antrodia camphorata negatively modulates JAK2/STAT3 signaling via microRNA let-7c and induces apoptosis in lung cancer cells.
  動物單一化合物Carcinogenesis201378 次引用
• Mushroom extracts and compounds with suppressive action on breast cancer: evidence from studies using cultured cancer cells, tumor-bearing animals, and clinical trials.
  綜述萃取物Applied microbiology and biotechnology202084 次引用
• Lanostanoids from fungi: a group of potential anticancer compounds.
  綜述萃取物Journal of natural products2012145 次引用
• Significance of Medicinal Mushrooms in Integrative Oncology: A Narrative Review.
  綜述萃取物Frontiers in pharmacology202074 次引用
• Antitumor effects of the partially purified polysaccharides from Antrodia camphorata and the mechanism of its action.
  動物菌絲體Toxicology and applied pharmacology2004131 次引用
• Analgesic and anti-inflammatory bioactivities of eburicoic acid and dehydroeburicoic acid isolated from Antrodia camphorata on the inflammatory mediator expression in mice.
  動物單一化合物Journal of agricultural and food chemistry201360 次引用

肝與代謝

這條線的文獻量最大之一（225 篇）。多數是動物模型。

• Antrodan Alleviates High-Fat and High-Fructose Diet-Induced Fatty Liver Disease in C57BL/6 Mice Model via AMPK/Sirt1/SREBP-1c/PPARγ Pathway.
  動物單一化合物International journal of molecular sciences2020159 次引用
• Antrodin A from Antrodia camphorata modulates the gut microbiome and liver metabolome in mice exposed to acute alcohol intake.
  動物菌絲體Food & function202172 次引用
• Antioxidative and hepatoprotective effects of Antrodia camphorata extract.
  動物萃取物Journal of agricultural and food chemistry2003245 次引用
• Triterpenoid-Rich Extract from Antrodia camphorata Improves Physical Fatigue and Exercise Performance in Mice.
  動物子實體Evidence-based complementary and alternative medicine : eCAM2012101 次引用
• Antroquinonol from ethanolic extract of mycelium of Antrodia cinnamomea protects hepatic cells from ethanol-induced oxidative stress through Nrf-2 activation.
  動物菌絲體Journal of ethnopharmacology2011108 次引用
• Recent research and development of Antrodia cinnamomea.
  綜述萃取物Pharmacology & therapeutics2013164 次引用
• Antrodin A from mycelium of Antrodia camphorata alleviates acute alcoholic liver injury and modulates intestinal flora dysbiosis in mice.
  動物菌絲體Journal of ethnopharmacology202054 次引用
• AGA induces sub-G1 cell cycle arrest and apoptosis in human colon cancer cells through p53-independent/p53-dependent pathway.
  動物萃取物BMC cancer202345 次引用

免疫與發炎

147 篇。

• The chemistry and biology of fungal meroterpenoids (2009-2019).
  綜述萃取物Organic & biomolecular chemistry2021110 次引用
• Antcin K inhibits VEGF‐dependent angiogenesis in human rheumatoid arthritis synovial fibroblasts
  動物單一化合物Journal of food biochemistry.202257 次引用
• Therapeutic potential of culinary-medicinal mushrooms for the management of neurodegenerative diseases: diversity, metabolite, and mechanism.
  綜述菌絲體Critical reviews in biotechnology2015143 次引用
• Ameliorative effects of Antrodia cinnamomea polysaccharides against cyclophosphamide-induced immunosuppression related to Nrf2/HO-1 signaling in BALB/c mice.
  動物萃取物International journal of biological macromolecules201858 次引用
• Antroquinonol mitigates an accelerated and progressive IgA nephropathy model in mice by activating the Nrf2 pathway and inhibiting T cells and NLRP3 inflammasome.
  動物菌絲體Free radical biology & medicine201378 次引用
• Antcin K inhibits VCAM-1-dependent monocyte adhesion in human rheumatoid arthritis synovial fibroblasts.
  動物單一化合物Food & nutrition research202241 次引用

粒線體、能量與老化

130 篇。骨幹是 AMPK → Sirt1 → PGC-1α 這條能量感測通路，也是老化研究的核心通路。

• Antrodia cinnamomea reduces obesity and modulates the gut microbiota in high-fat diet-fed mice.
  動物萃取物International journal of obesity (2005)201889 次引用
• Antrodia camphorata polysaccharide resists 6-OHDA-induced dopaminergic neuronal damage by inhibiting ROS-NLRP3 activation.
  動物萃取物Brain and behavior202044 次引用
• Effects of Antrodia camphorata and Panax ginseng supplementation on anti-fatigue properties in mice.
  動物萃取物The Journal of veterinary medical science201844 次引用
• Inhibition of ROS production, autophagy or apoptosis signaling reversed the anticancer properties of Antrodia salmonea in triple-negative breast cancer (MDA-MB-231) cells.
  動物萃取物Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association201746 次引用
• Hypoglycemic Efficacy of Docking Selected Natural Compounds against α-Glucosidase and α-Amylase.
  動物萃取物Molecules (Basel, Switzerland)201840 次引用
• Anti-Cancer Potential of Edible/Medicinal Mushrooms in Breast Cancer.
  綜述萃取物International journal of molecular sciences202349 次引用
• A steroid like phytochemical Antcin M is an anti-aging reagent that eliminates hyperglycemia-accelerated premature senescence in dermal fibroblasts by direct activation of Nrf2 and SIRT-1.
  動物單一化合物Oncotarget201642 次引用
• Coenzyme Q0 inhibited the NLRP3 inflammasome, metastasis/EMT, and Warburg effect by suppressing hypoxia-induced HIF-1α expression in HNSCC cells.
  動物萃取物International journal of biological sciences202427 次引用

安全性與毒理

46 篇。含基因毒性、致畸性與口服毒性評估。

• Protective effects of mycelia of Antrodia camphorata and Armillariella tabescens in submerged culture against ethanol-induced hepatic toxicity in rats.
  動物菌絲體Journal of ethnopharmacology200789 次引用
• Protective effects of fermented filtrate from Antrodia camphorata in submerged culture against CCl4-induced hepatic toxicity in rats.
  動物菌絲體Journal of agricultural and food chemistry2003116 次引用
• In vitro and in vivo comparisons of the effects of the fruiting body and mycelium of Antrodia camphorata against amyloid β-protein-induced neurotoxicity and memory impairment.
  動物子實體Applied microbiology and biotechnology201236 次引用
• Antrodia cinnamomea alleviates cisplatin-induced hepatotoxicity and enhances chemo-sensitivity of line-1 lung carcinoma xenografted in BALB/cByJ mice.
  動物萃取物Oncotarget201526 次引用
• A 90-day subchronic toxicological assessment of Antrodia cinnamomea in Sprague-Dawley rats.
  動物菌絲體Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association201128 次引用

神經

9 篇。這是相對少的一格。

• Fermented Antrodia cinnamomea extract protects rat PC12 cells from serum deprivation-induced apoptosis: the role of the MAPK family.
  動物萃取物Journal of agricultural and food chemistry200832 次引用
• Neuroprotective diterpenes from the fruiting body of Antrodia camphorata.
  細胞子實體Journal of natural products200690 次引用
• Current and further outlook on the protective potential of Antrodia camphorata against neurological disorders.
  綜述萃取物Frontiers in pharmacology20249 次引用